HL7 FHIR Implementation Guide Dossier Farmaceutico
0.1.1 - ci-build Italy flag

HL7 FHIR Implementation Guide Dossier Farmaceutico, published by HL7 Italia. This guide is not an authorized publication; it is the continuous build for version 0.1.1 built by the FHIR (HL7® FHIR® Standard) CI Build. This version is based on the current content of https://github.com/hl7-it/dossier-pharma/ and changes regularly. See the Directory of published versions

: AIFA - Indicazioni terapeutiche (Nota AIFA) - JSON Representation

Active as of 2024-06-24

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{
  "resourceType" : "CodeSystem",
  "id" : "aifa-nota",
  "text" : {
    "status" : "generated",
    "div" : "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p>This case-sensitive code system <code>http://hl7.it/fhir/dossier-pharma/CodeSystem/aifa-nota</code> defines the following codes:</p><table class=\"codes\"><tr><td style=\"white-space:nowrap\"><b>Code</b></td><td><b>Display</b></td></tr><tr><td style=\"white-space:nowrap\">01<a name=\"aifa-nota-01\"> </a></td><td>Farmaco in nota: pantoprazolo, omeprazolo, misoprostolo, lansoprazolo, esomeprazolo</td></tr><tr><td style=\"white-space:nowrap\">02<a name=\"aifa-nota-02\"> </a></td><td>Farmaco in nota: acido chenoursodesossicolico, acido tauroursodesossicolico, acido ursodesossicolico</td></tr><tr><td style=\"white-space:nowrap\">04<a name=\"aifa-nota-04\"> </a></td><td>Farmaco in nota: duloxetina, gabapentin, pregabalin</td></tr><tr><td style=\"white-space:nowrap\">08<a name=\"aifa-nota-08\"> </a></td><td>Farmaco in nota: levocarnitina</td></tr><tr><td style=\"white-space:nowrap\">11<a name=\"aifa-nota-11\"> </a></td><td>Farmaco in nota: Calcio folinato</td></tr><tr><td style=\"white-space:nowrap\">13<a name=\"aifa-nota-13\"> </a></td><td>Farmaci in Nota: Ipolipemizzanti:Fibrati: bezafibrato, fenofibrato, gemfibrozil\nStatine: simvastatina, pravastatina, fluvastatina, lovastatina, atorvastatina, rosuvastatina\nAltri: PUFA-N3, ezetimibe</td></tr><tr><td style=\"white-space:nowrap\">15<a name=\"aifa-nota-15\"> </a></td><td>Farmaco in nota: Albumina umana</td></tr><tr><td style=\"white-space:nowrap\">28<a name=\"aifa-nota-28\"> </a></td><td>Farmaco in nota: Megestrolo, Medrossiprogesterone</td></tr><tr><td style=\"white-space:nowrap\">31<a name=\"aifa-nota-31\"> </a></td><td>Farmaco in nota: Levodropropizina, Diidrocodeina  Acido benzoico, Diidrocodeina</td></tr><tr><td style=\"white-space:nowrap\">36<a name=\"aifa-nota-36\"> </a></td><td>Farmaco in nota: Testosterone</td></tr><tr><td style=\"white-space:nowrap\">39<a name=\"aifa-nota-39\"> </a></td><td>Farmaci in nota: somatropina, Somatrogon</td></tr><tr><td style=\"white-space:nowrap\">41<a name=\"aifa-nota-41\"> </a></td><td>Farmaco in nota: Calcitonina</td></tr><tr><td style=\"white-space:nowrap\">42<a name=\"aifa-nota-42\"> </a></td><td>Farmaco in nota: Acido etidronico, Acido clodronico</td></tr><tr><td style=\"white-space:nowrap\">48<a name=\"aifa-nota-48\"> </a></td><td>Farmaco in nota: Acido etidronico, Acido clodronico</td></tr><tr><td style=\"white-space:nowrap\">51<a name=\"aifa-nota-51\"> </a></td><td>Farmaci in nota: Analoghi del LHRH: Buserelina, Goserelina, Leuprorelina, Triptorelina Modulatori selettivi del Recettore del Progesterone: Ulipristal acetato Antagonisti dell ormone di rilascio delle gonadotropine, estrogeno e progestinico (in associazione): relugolix, estradiolo (come emiidrato) (E2), noretisterone acetato (NETA)</td></tr><tr><td style=\"white-space:nowrap\">55<a name=\"aifa-nota-55\"> </a></td><td>Farmaco in nota: Tobramicina, Piperacillina + Tazobactam, Piperacillina, Netilmicina, Mezlocillina, Gentamicina, Ceftazidima, Cefepime, Ampicillina + Sulbactam, Amikacina</td></tr><tr><td style=\"white-space:nowrap\">56<a name=\"aifa-nota-56\"> </a></td><td>Farmaco in nota: Teicoplanina, Rifabutina, Imipenem + Cilastatina, Aztreonam</td></tr><tr><td style=\"white-space:nowrap\">65<a name=\"aifa-nota-65\"> </a></td><td>Farmaco in nota: Glatiramer acetato - Interferone β-1a - Interferone β-1b - Teriflunomide - Dimetilfumarato - Peginterferone beta-1a</td></tr><tr><td style=\"white-space:nowrap\">66<a name=\"aifa-nota-66\"> </a></td><td>Farmaco in nota: Tenoxicam, Sulindac, Proglumetacina, Piroxicam, Oxaprozina, Nimesulide, Naprossene, Nabumetone, Meloxicam, Lornoxicam, Ketoprofene, Indometacina, Ibuprofene, Furprofene, Flurbiprofene, Fentiazac, Etoricoxib, Diclofenac + Misoprostolo, Diclofenac, Dexibuprofene, Codeina e ibuprofene, Cinnoxicam, Celecoxib, Amtolmetina, Acido tiaprofenico, Acido mefenamico, Acetametacina, Aceclofenac</td></tr><tr><td style=\"white-space:nowrap\">74<a name=\"aifa-nota-74\"> </a></td><td>Farmaco in nota: Urofollitropina, Menotropina, Lutropina alfa, Follitropina delta, Follitropina beta, Follitropina alfa/Lutropina alfa, Follitropina alfa, Coriogonadotropina alfa, Corifollitropina alfa</td></tr><tr><td style=\"white-space:nowrap\">75<a name=\"aifa-nota-75\"> </a></td><td>Farmaco in nota: Vardenafil, Tadalafil, Sildenafil, Avanafil, Alprostadil</td></tr><tr><td style=\"white-space:nowrap\">79<a name=\"aifa-nota-79\"> </a></td><td>Farmaci a carico SSN inclusi nella 79: Alendronato, Bazedoxifene, Denosumab, Ibandronato, Raloxifene, Risedronato, Romosozumab, Teriparatide, Zoledronato</td></tr><tr><td style=\"white-space:nowrap\">82<a name=\"aifa-nota-82\"> </a></td><td>Farmaco in nota: Zafirlukast, Montelukast</td></tr><tr><td style=\"white-space:nowrap\">83<a name=\"aifa-nota-83\"> </a></td><td>Farmaco in nota: Carbomer</td></tr><tr><td style=\"white-space:nowrap\">84<a name=\"aifa-nota-84\"> </a></td><td>Farmaco in nota: Valaciclovir, Famciclovir, Brivudina, Aciclovir</td></tr><tr><td style=\"white-space:nowrap\">85<a name=\"aifa-nota-85\"> </a></td><td>Farmaci a carico SSN inclusi nella 85: donepezil - galantamina - rivastigmina - memantina</td></tr><tr><td style=\"white-space:nowrap\">87<a name=\"aifa-nota-87\"> </a></td><td>Farmaci in Nota: fesoterodina, ossibutina, solifenacina, tolterodina</td></tr><tr><td style=\"white-space:nowrap\">88<a name=\"aifa-nota-88\"> </a></td><td>Farmaco in nota: Corticosteroidi, preparati dermatologici</td></tr><tr><td style=\"white-space:nowrap\">89<a name=\"aifa-nota-89\"> </a></td><td>Farmaco in nota: Prometazina, Oxatomide, Mizolastina, Loratadina, Levocetirizina, Ketotifene, Fexofenadina, Ebastina, Desloratadina, Cetirizina, Acrivastina, Rupatadina</td></tr><tr><td style=\"white-space:nowrap\">90<a name=\"aifa-nota-90\"> </a></td><td>Farmaco in nota: Naloxegol, Metilnaltrexone, Naldemedina</td></tr><tr><td style=\"white-space:nowrap\">91<a name=\"aifa-nota-91\"> </a></td><td>Farmaco in nota: Febuxostat</td></tr><tr><td style=\"white-space:nowrap\">92<a name=\"aifa-nota-92\"> </a></td><td>Farmaco in nota: Benzilpenicillina benzatinica</td></tr><tr><td style=\"white-space:nowrap\">93<a name=\"aifa-nota-93\"> </a></td><td>Farmaco in nota: Midazolam oromucosale</td></tr><tr><td style=\"white-space:nowrap\">95<a name=\"aifa-nota-95\"> </a></td><td>Farmaci in Nota : diclofenac 3% in ialuronato di sodio, 5-Fluorouracile/Acido salicilico (per la cheratosi attinica); Imiquimod crema 3,75%, 5-Fluorouracile 4%, Tirbanibulina 10 mg/g unguento (per la cheratosi attinica non ipercheratosica non ipertrofica).</td></tr><tr><td style=\"white-space:nowrap\">96<a name=\"aifa-nota-96\"> </a></td><td>Farmaci in Nota: colecalciferolo, colecalciferolo/Sali di calcio, calcifediolo</td></tr><tr><td style=\"white-space:nowrap\">97<a name=\"aifa-nota-97\"> </a></td><td>Farmaci in Nota:  AVK : Warfarin, Acenocumarolo -  NAO/DOAC : Dabigatran, Apixaban, Edoxaban, Rivaroxaban</td></tr><tr><td style=\"white-space:nowrap\">98<a name=\"aifa-nota-98\"> </a></td><td>Farmaci in nota: aflibercept ,  bevacizumab (L. 648/96), brolucizumab, faricimab, ranibizumab</td></tr><tr><td style=\"white-space:nowrap\">99<a name=\"aifa-nota-99\"> </a></td><td>Farmaci in Nota : medicinali per uso inalatorio (limitatamente ai dosaggi/formulazioni autorizzati per la terapia inalatoria di mantenimento della BPCO) a base dei seguenti principi attivi:  LABA : Formoterolo, Indacaterolo, Olodaterolo, Salmeterolo -  LAMA : Aclidinio, Glicopirronio, Tiotropio, Umeclidinio -  LABA + ICS  (unico erogatore) - Formoterolo/Beclometasone, Formoterolo/Budesonide, Salmeterolo/Fluticasone Propionato, Vilanterolo/Fluticasone Furoato -  LABA + LAMA  (unico erogatore): Indacaterolo/Glicopirronio, Vilanterolo/Umeclidinio, Olodaterolo/Tiotropio, Formoterolo/Aclidinio -  ICS + LABA + LAMA  (unico erogatore): Beclometasone Dipropionato/Formoterolo Fumarato Diidrato/Glicopirronio Bromuro, Fluticasone Furoato/ Umeclidinio Bromuro/ Vilanterolo Trifenatato, Budesonide/glicopirronio bromuro/ formoterolo fumarato diidrato.</td></tr><tr><td style=\"white-space:nowrap\">100<a name=\"aifa-nota-100\"> </a></td><td>Farmaci in Nota: INIBITORI SGLT2: canagliflozin - dapagliflozin - empagliflozin - ertugliflozin\nAGONISTI RECETTORIALI GLP1: dulaglutide - exenatide - exenatide LAR - liraglutide - lixisenatide - semaglutide orale - semaglutide sottocutanea\nINIBITORI DPP4: alogliptin - linagliptin - saxagliptin - sitagliptin - vildagliptin\nASSOCIAZIONI PRECOSTITUITE: canagliflozin/metformina - dapagliflozin/metformina - empagliflozin/metformina - empagliflozin/linagliptin - ertugliflozin/metformina - ertugliflozin/sitagliptin - saxagliptin/dapagliflozin - degludec/liraglutide - glargine/lixisenatide - alogliptin/metformina - alogliptin/pioglitazone - linagliptin/metformina - saxagliptin/metformina - sitagliptin/metformina - vildagliptin/metformina</td></tr><tr><td style=\"white-space:nowrap\">101<a name=\"aifa-nota-101\"> </a></td><td>Farmaci in Nota: Anticoagulanti orali inibitori della vitamina K (AVK): warfarin - acenocumarolo\nInibitori diretti della trombina o del fattore Xa (NAO/DOAC): dabigatran - apixaban - edoxaban - rivaroxaban</td></tr></table></div>"
  },
  "url" : "http://hl7.it/fhir/dossier-pharma/CodeSystem/aifa-nota",
  "version" : "0.1.1",
  "name" : "CsAifaNota",
  "title" : "AIFA - Indicazioni terapeutiche (Nota AIFA)",
  "status" : "active",
  "experimental" : false,
  "date" : "2024-06-24T07:51:34+00:00",
  "publisher" : "HL7 Italia",
  "contact" : [
    {
      "name" : "HL7 Italia",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://hl7.it"
        }
      ]
    },
    {
      "name" : "HL7 Italia",
      "telecom" : [
        {
          "system" : "url",
          "value" : "https://hl7.it"
        }
      ]
    }
  ],
  "description" : "AIFA - Indicazioni terapeutiche per le quali un determinato farmaco è rimborsabile a carico del Servizio Sanitario Nazionale. Conosciute come Note AIFA.",
  "jurisdiction" : [
    {
      "coding" : [
        {
          "system" : "urn:iso:std:iso:3166",
          "code" : "IT",
          "display" : "Italy"
        }
      ]
    }
  ],
  "caseSensitive" : true,
  "content" : "complete",
  "count" : 40,
  "concept" : [
    {
      "code" : "01",
      "display" : "Farmaco in nota: pantoprazolo, omeprazolo, misoprostolo, lansoprazolo, esomeprazolo"
    },
    {
      "code" : "02",
      "display" : "Farmaco in nota: acido chenoursodesossicolico, acido tauroursodesossicolico, acido ursodesossicolico"
    },
    {
      "code" : "04",
      "display" : "Farmaco in nota: duloxetina, gabapentin, pregabalin"
    },
    {
      "code" : "08",
      "display" : "Farmaco in nota: levocarnitina"
    },
    {
      "code" : "11",
      "display" : "Farmaco in nota: Calcio folinato"
    },
    {
      "code" : "13",
      "display" : "Farmaci in Nota: Ipolipemizzanti:Fibrati: bezafibrato, fenofibrato, gemfibrozil\nStatine: simvastatina, pravastatina, fluvastatina, lovastatina, atorvastatina, rosuvastatina\nAltri: PUFA-N3, ezetimibe"
    },
    {
      "code" : "15",
      "display" : "Farmaco in nota: Albumina umana"
    },
    {
      "code" : "28",
      "display" : "Farmaco in nota: Megestrolo, Medrossiprogesterone"
    },
    {
      "code" : "31",
      "display" : "Farmaco in nota: Levodropropizina, Diidrocodeina  Acido benzoico, Diidrocodeina"
    },
    {
      "code" : "36",
      "display" : "Farmaco in nota: Testosterone"
    },
    {
      "code" : "39",
      "display" : "Farmaci in nota: somatropina, Somatrogon"
    },
    {
      "code" : "41",
      "display" : "Farmaco in nota: Calcitonina"
    },
    {
      "code" : "42",
      "display" : "Farmaco in nota: Acido etidronico, Acido clodronico"
    },
    {
      "code" : "48",
      "display" : "Farmaco in nota: Acido etidronico, Acido clodronico"
    },
    {
      "code" : "51",
      "display" : "Farmaci in nota: Analoghi del LHRH: Buserelina, Goserelina, Leuprorelina, Triptorelina Modulatori selettivi del Recettore del Progesterone: Ulipristal acetato Antagonisti dell ormone di rilascio delle gonadotropine, estrogeno e progestinico (in associazione): relugolix, estradiolo (come emiidrato) (E2), noretisterone acetato (NETA)"
    },
    {
      "code" : "55",
      "display" : "Farmaco in nota: Tobramicina, Piperacillina + Tazobactam, Piperacillina, Netilmicina, Mezlocillina, Gentamicina, Ceftazidima, Cefepime, Ampicillina + Sulbactam, Amikacina"
    },
    {
      "code" : "56",
      "display" : "Farmaco in nota: Teicoplanina, Rifabutina, Imipenem + Cilastatina, Aztreonam"
    },
    {
      "code" : "65",
      "display" : "Farmaco in nota: Glatiramer acetato - Interferone β-1a - Interferone β-1b - Teriflunomide - Dimetilfumarato - Peginterferone beta-1a"
    },
    {
      "code" : "66",
      "display" : "Farmaco in nota: Tenoxicam, Sulindac, Proglumetacina, Piroxicam, Oxaprozina, Nimesulide, Naprossene, Nabumetone, Meloxicam, Lornoxicam, Ketoprofene, Indometacina, Ibuprofene, Furprofene, Flurbiprofene, Fentiazac, Etoricoxib, Diclofenac + Misoprostolo, Diclofenac, Dexibuprofene, Codeina e ibuprofene, Cinnoxicam, Celecoxib, Amtolmetina, Acido tiaprofenico, Acido mefenamico, Acetametacina, Aceclofenac"
    },
    {
      "code" : "74",
      "display" : "Farmaco in nota: Urofollitropina, Menotropina, Lutropina alfa, Follitropina delta, Follitropina beta, Follitropina alfa/Lutropina alfa, Follitropina alfa, Coriogonadotropina alfa, Corifollitropina alfa"
    },
    {
      "code" : "75",
      "display" : "Farmaco in nota: Vardenafil, Tadalafil, Sildenafil, Avanafil, Alprostadil"
    },
    {
      "code" : "79",
      "display" : "Farmaci a carico SSN inclusi nella 79: Alendronato, Bazedoxifene, Denosumab, Ibandronato, Raloxifene, Risedronato, Romosozumab, Teriparatide, Zoledronato"
    },
    {
      "code" : "82",
      "display" : "Farmaco in nota: Zafirlukast, Montelukast"
    },
    {
      "code" : "83",
      "display" : "Farmaco in nota: Carbomer"
    },
    {
      "code" : "84",
      "display" : "Farmaco in nota: Valaciclovir, Famciclovir, Brivudina, Aciclovir"
    },
    {
      "code" : "85",
      "display" : "Farmaci a carico SSN inclusi nella 85: donepezil - galantamina - rivastigmina - memantina"
    },
    {
      "code" : "87",
      "display" : "Farmaci in Nota: fesoterodina, ossibutina, solifenacina, tolterodina"
    },
    {
      "code" : "88",
      "display" : "Farmaco in nota: Corticosteroidi, preparati dermatologici"
    },
    {
      "code" : "89",
      "display" : "Farmaco in nota: Prometazina, Oxatomide, Mizolastina, Loratadina, Levocetirizina, Ketotifene, Fexofenadina, Ebastina, Desloratadina, Cetirizina, Acrivastina, Rupatadina"
    },
    {
      "code" : "90",
      "display" : "Farmaco in nota: Naloxegol, Metilnaltrexone, Naldemedina"
    },
    {
      "code" : "91",
      "display" : "Farmaco in nota: Febuxostat"
    },
    {
      "code" : "92",
      "display" : "Farmaco in nota: Benzilpenicillina benzatinica"
    },
    {
      "code" : "93",
      "display" : "Farmaco in nota: Midazolam oromucosale"
    },
    {
      "code" : "95",
      "display" : "Farmaci in Nota : diclofenac 3% in ialuronato di sodio, 5-Fluorouracile/Acido salicilico (per la cheratosi attinica); Imiquimod crema 3,75%, 5-Fluorouracile 4%, Tirbanibulina 10 mg/g unguento (per la cheratosi attinica non ipercheratosica non ipertrofica)."
    },
    {
      "code" : "96",
      "display" : "Farmaci in Nota: colecalciferolo, colecalciferolo/Sali di calcio, calcifediolo"
    },
    {
      "code" : "97",
      "display" : "Farmaci in Nota:  AVK : Warfarin, Acenocumarolo -  NAO/DOAC : Dabigatran, Apixaban, Edoxaban, Rivaroxaban"
    },
    {
      "code" : "98",
      "display" : "Farmaci in nota: aflibercept ,  bevacizumab (L. 648/96), brolucizumab, faricimab, ranibizumab"
    },
    {
      "code" : "99",
      "display" : "Farmaci in Nota : medicinali per uso inalatorio (limitatamente ai dosaggi/formulazioni autorizzati per la terapia inalatoria di mantenimento della BPCO) a base dei seguenti principi attivi:  LABA : Formoterolo, Indacaterolo, Olodaterolo, Salmeterolo -  LAMA : Aclidinio, Glicopirronio, Tiotropio, Umeclidinio -  LABA + ICS  (unico erogatore) - Formoterolo/Beclometasone, Formoterolo/Budesonide, Salmeterolo/Fluticasone Propionato, Vilanterolo/Fluticasone Furoato -  LABA + LAMA  (unico erogatore): Indacaterolo/Glicopirronio, Vilanterolo/Umeclidinio, Olodaterolo/Tiotropio, Formoterolo/Aclidinio -  ICS + LABA + LAMA  (unico erogatore): Beclometasone Dipropionato/Formoterolo Fumarato Diidrato/Glicopirronio Bromuro, Fluticasone Furoato/ Umeclidinio Bromuro/ Vilanterolo Trifenatato, Budesonide/glicopirronio bromuro/ formoterolo fumarato diidrato."
    },
    {
      "code" : "100",
      "display" : "Farmaci in Nota: INIBITORI SGLT2: canagliflozin - dapagliflozin - empagliflozin - ertugliflozin\nAGONISTI RECETTORIALI GLP1: dulaglutide - exenatide - exenatide LAR - liraglutide - lixisenatide - semaglutide orale - semaglutide sottocutanea\nINIBITORI DPP4: alogliptin - linagliptin - saxagliptin - sitagliptin - vildagliptin\nASSOCIAZIONI PRECOSTITUITE: canagliflozin/metformina - dapagliflozin/metformina - empagliflozin/metformina - empagliflozin/linagliptin - ertugliflozin/metformina - ertugliflozin/sitagliptin - saxagliptin/dapagliflozin - degludec/liraglutide - glargine/lixisenatide - alogliptin/metformina - alogliptin/pioglitazone - linagliptin/metformina - saxagliptin/metformina - sitagliptin/metformina - vildagliptin/metformina"
    },
    {
      "code" : "101",
      "display" : "Farmaci in Nota: Anticoagulanti orali inibitori della vitamina K (AVK): warfarin - acenocumarolo\nInibitori diretti della trombina o del fattore Xa (NAO/DOAC): dabigatran - apixaban - edoxaban - rivaroxaban"
    }
  ]
}